diff --git a/actionview/CHANGELOG.md b/actionview/CHANGELOG.md
index b1ef9625b6d5660425916735a932a121bb254700..ecbc3fa5ecdd3a7f3194a1537e6342474d63361d 100644
--- a/actionview/CHANGELOG.md
+++ b/actionview/CHANGELOG.md
@@ -1,3 +1,9 @@
+*   Allow programmatic click events to trigger Rails UJS click handlers.
+    Programmatic click events (eg. ones generated by `Rails.fire(link, "click")`) don't specify a button. These events were being incorrectly stopped by code meant to ignore scroll wheel and right clicks introduced in #34573.
+
+    *Sudara Williams*
+
+
 ## Rails 5.2.3 (March 27, 2019) ##
 
 *   Prevent non-primary mouse keys from triggering Rails UJS click handlers.
diff --git a/actionview/app/assets/javascripts/rails-ujs/features/remote.coffee b/actionview/app/assets/javascripts/rails-ujs/features/remote.coffee
index a5b61220bba9b25a94589969f7360b49531fa87f..d1aeef56c7383de62be6c22f3cd5f37c0628dc70 100644
--- a/actionview/app/assets/javascripts/rails-ujs/features/remote.coffee
+++ b/actionview/app/assets/javascripts/rails-ujs/features/remote.coffee
@@ -88,6 +88,6 @@ Rails.preventInsignificantClick = (e) ->
   data = link.getAttribute('data-params')
   metaClick = e.metaKey or e.ctrlKey
   insignificantMetaClick = metaClick and method is 'GET' and not data
-  primaryMouseKey = e.button is 0
-  e.stopImmediatePropagation() if not primaryMouseKey or insignificantMetaClick
+  nonPrimaryMouseClick = e.button? and e.button isnt 0
+  e.stopImmediatePropagation() if nonPrimaryMouseClick or insignificantMetaClick
 
diff --git a/actionview/test/ujs/public/test/data-remote.js b/actionview/test/ujs/public/test/data-remote.js
index 55d39b0a520aee75e71e740191113a3ccb7cfebc..f5215b175db3da983871d56e092cd35e0705d141 100644
--- a/actionview/test/ujs/public/test/data-remote.js
+++ b/actionview/test/ujs/public/test/data-remote.js
@@ -82,6 +82,20 @@ asyncTest('right/mouse-wheel-clicking on a link does not fire ajaxyness', 0, fun
   setTimeout(function() { start() }, 13)
 })
 
+asyncTest('clicking on a link via a non-mouse Event (such as from js) works', 1, function() {
+  var link = $('a[data-remote]')
+
+  link
+    .removeAttr('data-params')
+    .bindNative('ajax:beforeSend', function() {
+      ok(true, 'ajax should be triggered')
+    })
+
+  Rails.fire(link[0], 'click')
+
+  setTimeout(function() { start() }, 13)
+})
+
 asyncTest('ctrl-clicking on a link still fires ajax for non-GET links and for links with "data-params"', 2, function() {
   var link = $('a[data-remote]')